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Page 1
Did you mean motor and brain (185,494 results)?
Are MTHFR C677T and MTRR A66G Polymorphisms Associated with Overweight/Obesity Risk? From a Case-Control to a Meta-Analysis of 30,327 Subjects.
Fan SJ, Yang BY, Zhi XY, He M, Wang D, Wang YX, Wang YN, Wei J, Zheng QM, Sun GF. Fan SJ, et al. Int J Mol Sci. 2015 May 26;16(6):11849-63. doi: 10.3390/ijms160611849. Int J Mol Sci. 2015. PMID: 26016497 Free PMC article.
Similarly, both the case-control study and meta-analysis found no significant association between the MTRR A66G polymorphism and being overweight/obesity. However, sensitivity analyses showed that the associations between the MTRR A66G polymorphism and being overwei …
Similarly, both the case-control study and meta-analysis found no significant association between the MTRR A66G polymorphism and bein …
Associations of MTHFR C677T and MTRR A66G gene polymorphisms with metabolic syndrome: a case-control study in Northern China.
Yang B, Fan S, Zhi X, Wang D, Li Y, Wang Y, Wang Y, Wei J, Zheng Q, Sun G. Yang B, et al. Int J Mol Sci. 2014 Nov 25;15(12):21687-702. doi: 10.3390/ijms151221687. Int J Mol Sci. 2014. PMID: 25429430 Free PMC article.
The MTRR A66G polymorphism was associated with an increased risk of MetS when combined with the MTHFR 677TT genotype, although there was no association found between MetS and MTRR A66G alone. Furthermore, the MTRR 66GG genotype was associated with high fastin …
The MTRR A66G polymorphism was associated with an increased risk of MetS when combined with the MTHFR 677TT genotype, although there …
Additive Interaction of MTHFR C677T and MTRR A66G Polymorphisms with Being Overweight/Obesity on the Risk of Type 2 Diabetes.
Zhi X, Yang B, Fan S, Li Y, He M, Wang D, Wang Y, Wei J, Zheng Q, Sun G. Zhi X, et al. Int J Environ Res Public Health. 2016 Dec 15;13(12):1243. doi: 10.3390/ijerph13121243. Int J Environ Res Public Health. 2016. PMID: 27983710 Free PMC article.
Although both methylenetetrahydrofolate reductase (MTHFR) C677T and methionine synthase reductase (MTRR) A66G polymorphisms have been associated with type 2 diabetes (T2D), their interactions with being overweight/obesity on T2D risk remain unclear. ...Our findings suggest …
Although both methylenetetrahydrofolate reductase (MTHFR) C677T and methionine synthase reductase (MTRR) A66G polymorphisms have been …
Folate pathway gene polymorphisms and risk of childhood brain tumors: results from an Australian case-control study.
Greenop KR, Scott RJ, Attia J, Bower C, de Klerk NH, Norris MD, Haber M, Jamieson SE, van Bockxmeer FM, Gottardo NG, Ashton LJ, Armstrong BK, Milne E. Greenop KR, et al. Cancer Epidemiol Biomarkers Prev. 2015 Jun;24(6):931-7. doi: 10.1158/1055-9965.EPI-14-1248. Epub 2015 Mar 25. Cancer Epidemiol Biomarkers Prev. 2015. PMID: 25809864
Six polymorphisms were genotyped in children and parents (MTHFR 677C>T, MTHFR 1298A>C, MTRR 66A>G, MTR 2756A>G, MTR 5049C>A, and CBS 2199 T>C). Maternal folic acid use was ascertained via questionnaire. ...IMPACT: The possible interaction between folic ac …
Six polymorphisms were genotyped in children and parents (MTHFR 677C>T, MTHFR 1298A>C, MTRR 66A>G, MTR 2756A>G, MTR 5049C …
Gender-specific interactions of MTHFR C677T and MTRR A66G polymorphisms with overweight/obesity on serum lipid levels in a Chinese Han population.
Zhi X, Yang B, Fan S, Wang Y, Wei J, Zheng Q, Sun G. Zhi X, et al. Lipids Health Dis. 2016 Oct 28;15(1):185. doi: 10.1186/s12944-016-0354-9. Lipids Health Dis. 2016. PMID: 27793164 Free PMC article.
BACKGROUND: Little is known regarding the interactions of methylenetetrahydrofolate reductase (MTHFR) C677T and methionine synthase reductase (MTRR) A66G polymorphisms with overweight/obesity on serum lipid profiles. ...For female subjects with overweight/obesity, the seru …
BACKGROUND: Little is known regarding the interactions of methylenetetrahydrofolate reductase (MTHFR) C677T and methionine synthase reductas …
Polymorphisms in Maternal Selected Folate Metabolism-Related Genes in Neural Tube Defect-Affected Pregnancy.
Dewelle WK, Melka DS, Aklilu AT, Gebremariam MY, Alemayehu MA, Alemayehu DH, Woldemichael TS, Gebre SG. Dewelle WK, et al. Adv Biomed Res. 2023 Jun 30;12:160. doi: 10.4103/abr.abr_103_22. eCollection 2023. Adv Biomed Res. 2023. PMID: 37564453 Free PMC article.
BACKGROUND: Neural tube defects (NTDs) are abnormalities of the brain and spinal cord, which occur as a result of failure in neural tube closure during embryogenesis. ...In this study, the role of polymorphisms in MTHFR 677C > T (rs1801133), MTHFR 1298A > C (rs180113 …
BACKGROUND: Neural tube defects (NTDs) are abnormalities of the brain and spinal cord, which occur as a result of failure in neural t …
Mouse model for deficiency of methionine synthase reductase exhibits short-term memory impairment and disturbances in brain choline metabolism.
Jadavji NM, Bahous RH, Deng L, Malysheva O, Grand'maison M, Bedell BJ, Caudill MA, Rozen R. Jadavji NM, et al. Biochem J. 2014 Jul 15;461(2):205-12. doi: 10.1042/BJ20131568. Biochem J. 2014. PMID: 24800750
Hyperhomocysteinaemia can contribute to cognitive impairment and brain atrophy. MTRR (methionine synthase reductase) activates methionine synthase, which catalyses homocysteine remethylation to methionine. ...The goal of the present study was to determine whether mi …
Hyperhomocysteinaemia can contribute to cognitive impairment and brain atrophy. MTRR (methionine synthase reductase) activates …
"Polymorphisms in folate metabolism genes as maternal risk factor for neural tube defects: an updated meta-analysis".
Yadav U, Kumar P, Yadav SK, Mishra OP, Rai V. Yadav U, et al. Metab Brain Dis. 2015 Feb;30(1):7-24. doi: 10.1007/s11011-014-9575-7. Epub 2014 Jul 9. Metab Brain Dis. 2015. PMID: 25005003 Review.
Epidemiological studies have evaluated the association between maternal methylenetetrahydrofolate reductase (MTHFR) C677T, A1298C and methionine synthase reductase (MTRR) A66G polymorphisms and risk of neural tube defects (NTDs) in offspring. ...In conclusion, present meta …
Epidemiological studies have evaluated the association between maternal methylenetetrahydrofolate reductase (MTHFR) C677T, A1298C and methio …
Association of homocysteine (but not of MTHFR 677 C>T, MTR 2756 A>G, MTRR 66 A>G and TCN2 776 C>G) with ischaemic cerebrovascular disease in Sicily.
Bosco P, Guéant-Rodriguez RM, Anello G, Spada R, Romano A, Fajardo A, Caraci F, Ferri R, Guéant JL. Bosco P, et al. Thromb Haemost. 2006 Aug;96(2):154-9. Thromb Haemost. 2006. PMID: 16894458
The association of 2756 A>G of methionine synthase (MTR), 66 A>G of methionine synthase reductase (MTRR) and 776 C>G of transcobalamin ( TCN2 ) needs to be evaluated further. ...In multivariate analysis, t-Hcys was a significant independent predictor of iCVD with …
The association of 2756 A>G of methionine synthase (MTR), 66 A>G of methionine synthase reductase (MTRR) and 776 C>G of tran …
Methionine synthase (MTR) 2756 (A --> G) polymorphism, double heterozygosity methionine synthase 2756 AG/methionine synthase reductase (MTRR) 66 AG, and elevated homocysteinemia are three risk factors for having a child with Down syndrome.
Bosco P, Guéant-Rodriguez RM, Anello G, Barone C, Namour F, Caraci F, Romano A, Romano C, Guéant JL. Bosco P, et al. Am J Med Genet A. 2003 Sep 1;121A(3):219-24. doi: 10.1002/ajmg.a.20234. Am J Med Genet A. 2003. PMID: 12923861
Contradictory findings have been recently published on the evaluation of genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR 677 C-->T) and methionine synthase reductase (MTRR 66 A-->G) as risk factors for having a child with Down syndrome (DS); howev …
Contradictory findings have been recently published on the evaluation of genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR …
31 results